{"product_id":"lim-and-sh3-domain-protein-1-rabbit-pab-es8817","title":"LIM and SH3 domain protein 1 rabbit pAb - ES8817","description":"\u003cp\u003eLIM and SH3 domain protein 1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8817-50, ES8817-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 38kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3927\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q14847\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Associated with the F-actin rich cortical cytoskeleton.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202390876339,"sku":"ES8817-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202390909107,"sku":"ES8817-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_ae607eec-e129-47c9-97de-28ff0a73bf0a.png?v=1767128127","url":"https:\/\/afsbio.com\/products\/lim-and-sh3-domain-protein-1-rabbit-pab-es8817","provider":"AFSBio Inc.","version":"1.0","type":"link"}