{"product_id":"lin28a-9g2-monoclonal-antibody-mb3144","title":"LIN28A (9G2) Monoclonal Antibody-MB3144","description":"\u003cp\u003eLIN28A (9G2) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3144-50, MB3144-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9H9Z2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11\/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 23 kDa; Observed MW: 23 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunofluorescence analysis of LIN28A in Hela cells were transfected with pMX construct of Human LIN28 using LIN28A antibody, Immunofluorescence analysis of LIN28A in NTERA-2 cells using LIN28A antibody. Blue: DRAQ5 fluorescent DNA dye., Western blot analysis of LIN28A in NTERA-2 lysates using LIN28A antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999926456499,"sku":"MB3144-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999926489267,"sku":"MB3144-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1a655a69-dca1-48e3-9a37-0515a049a9cc.jpg?v=1706358175","url":"https:\/\/afsbio.com\/products\/lin28a-9g2-monoclonal-antibody-mb3144","provider":"AFSBio Inc.","version":"1.0","type":"link"}