{"product_id":"litaf-polyclonal-antibody-ra33092","title":"LITAF Polyclonal Antibody - RA33092","description":"LITAF Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA33092-50, RA33092-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: lipopolysaccharide induced TNF factor (LITAF) Homo sapiens Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014],\n\nCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 9516\n\nProtein MW (KDa): 17\n\nSWISS: Q99732\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120504004787,"sku":"RA33092-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120504037555,"sku":"RA33092-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b281aec5-a583-431c-bc40-3a9a6621ae60.png?v=1773366804","url":"https:\/\/afsbio.com\/products\/litaf-polyclonal-antibody-ra33092","provider":"AFSBio Inc.","version":"1.0","type":"link"}