{"product_id":"lmtk3-polyclonal-antibody-bt-ap05045","title":"LMTK3 Polyclonal Antibody - BT-AP05045","description":"\u003cp\u003eLMTK3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05045-20, BT-AP05045-50, BT-AP05045-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LMTK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LMTK3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 153661\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96Q04; Mouse: Q5XJV6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LMTK3; KIAA1883; TYKLM3; Serine\/threonine-protein kinase LMTK3; Lemur tyrosine kinase 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 114783; Mouse: 381983\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239663984819,"sku":"BT-AP05045-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239664017587,"sku":"BT-AP05045-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239664050355,"sku":"BT-AP05045-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3e296263-395a-40a5-b56e-0f6059d7d28d.png?v=1769397766","url":"https:\/\/afsbio.com\/products\/lmtk3-polyclonal-antibody-bt-ap05045","provider":"AFSBio Inc.","version":"1.0","type":"link"}