{"product_id":"lmx1b-d159-polyclonal-antibody-bs2457","title":"LMX1B (D159) Polyclonal Antibody-BS2457","description":"\u003cp\u003eLMX1B (D159) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2457-50, BS2457-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O60663\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IHC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Lim class homeobox gene Lmx1b is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: LMX1B (D159) polyclonal antibody detects endogenous levels of LMX1B protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of LMX1B (D159) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:HEK293T whole cell lysate\u003cbr\u003e\nLane2:Raw264.7 whole cell lysate\u003cbr\u003e\nLane3:PC12 whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: LIM homeobox transcription factor 1-beta; LIM\/homeobox protein 1.2; LMX-1.2; LIM\/homeobox protein LMX1B; LMX1B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 131-180 of Human LMX1B.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910481940659,"sku":"BS2457-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910481973427,"sku":"BS2457-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e8bbdac2-ad65-422f-92c7-0a53811a6d79.jpg?v=1703093348","url":"https:\/\/afsbio.com\/products\/lmx1b-d159-polyclonal-antibody-bs2457","provider":"AFSBio Inc.","version":"1.0","type":"link"}