{"product_id":"lphn1-polyclonal-antibody-bs65810","title":"LPHN1 Polyclonal Antibody-BS65810","description":"LPHN1 Polyclonal Antibody\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers: BS65810-50, BS65810-100\n\nProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\n\nSwiss-Prot: O94910\n\nHost: Rabbit\n\nReactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,\n\nApplications: IHC-P\n\nAll Applications: IHC-P=1:100-500\n\nBackground: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin\/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]\n\nPurification and Purity: affinity purified by Protein A\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -17°C long term. Avoid freeze-thaw cycles.\n\nSpecificity: LPHN1 Polyclonal Antibody detects endogenous levels of LPHN1 protein.\n\nBioworld Molecular Weight: ~160 kDa\n\nNote: For research use only, not for use in diagnostic procedure.\n\nExtra Notes: Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes;Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LPHN1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C\n\nAlternative Name: Calcium independent alpha latrotoxin receptor 1; Calcium-independent alpha-latrotoxin receptor 1; CIRL-1; CIRL1; CL1; CLIBA; G protein-coupled receptor for alpha-Latrotoxin; KIAA0821; Latrophilin 1; Latrophilin-1; Latrophilin1; LEC2; Lectomedin 2; Lectomedin-2; LPHN 1; LPHN1; LPHN1_HUMAN.\n\nImmunogen: KLH conjugated synthetic peptide derived from human LPHN1:201-300\/1474\u003cextracellular\u003e\n\nConjugate: Unconjugated\n\nModification: Unmodified\u003c\/extracellular\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044013342899,"sku":"BS65810-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044013408435,"sku":"BS65810-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5eb30d0a-37a6-41ad-9cd0-0c5be198fad2.jpg?v=1707738412","url":"https:\/\/afsbio.com\/products\/lphn1-polyclonal-antibody-bs65810","provider":"AFSBio Inc.","version":"1.0","type":"link"}