{"product_id":"lrat-rabbit-pab-es2724","title":"LRAT rabbit pAb - ES2724","description":"\u003cp\u003eLRAT rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2724-50, ES2724-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT) Homo sapiens The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human LRAT. AA range:111-160\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 27kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9227\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O95237\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum. Endosome, multivesicular body. Cytoplasm, perinuclear region. Present in the rough endoplasmic reticulum and multivesicular body in hepatic stellate cells. Present in the rough endoplasmic reticulum and perinuclear region in endothelial cells (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202093703347,"sku":"ES2724-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202093736115,"sku":"ES2724-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_5f8a6ebe-e5ea-4d55-8d31-058ab063efd0.png?v=1767121728","url":"https:\/\/afsbio.com\/products\/lrat-rabbit-pab-es2724","provider":"AFSBio Inc.","version":"1.0","type":"link"}