{"product_id":"lrig3-polyclonal-antibody-e-ab-12545","title":"LRIG3 Polyclonal Antibody - E-AB-12545","description":"\u003cp\u003eLRIG3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-12545-60, E-AB-12545-120, E-AB-12545-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: LRIG3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Leucine-rich repeats and immunoglobulin-like domains protein 3; Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3; LIG-3; LIG3; LRIG1-3; Lrig3; LRIG3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Developmental Biology, Neuroscience, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q6UXM1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.Lrig3was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition ofLrig3expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human LRIG3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124092829875,"sku":"E-AB-12545-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124092862643,"sku":"E-AB-12545-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124092895411,"sku":"E-AB-12545-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_33092c46-2eb6-4dd1-8669-c28aa4a08e4e.png?v=1709723837","url":"https:\/\/afsbio.com\/products\/lrig3-polyclonal-antibody-e-ab-12545","provider":"AFSBio Inc.","version":"1.0","type":"link"}