{"product_id":"lrp5-monoclonal-antibody-bt-mca3804","title":"LRP5 Monoclonal Antibody - BT-MCA3804","description":"\u003cp\u003eLRP5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3804-50, BT-MCA3804-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Metabolism, Neuroscience , Signal transduction, Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LRP5\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2B11\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LRP5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human LRP5 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 179kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O75197\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4041\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238586540211,"sku":"BT-MCA3804-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238586572979,"sku":"BT-MCA3804-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d8e5587a-3f43-41c0-a5fa-d42ab5a37778.png?v=1769382833","url":"https:\/\/afsbio.com\/products\/lrp5-monoclonal-antibody-bt-mca3804","provider":"AFSBio Inc.","version":"1.0","type":"link"}