{"product_id":"lrrc41-rabbit-pab-es2726","title":"LRRC41 rabbit pAb - ES2726","description":"\u003cp\u003eLRRC41 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2726-50, ES2726-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: caution:It is uncertain whether Met-1 or Met-23 is the initiator., domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x (3)-C-x (3)-[AILV]., function:Probable substrate recognition component of an ECS (Elongin BC-CUL2\/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally extended., similarity:Contains 7 LRR (leucine-rich) repeats., subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS (LRRC41) complex which contains CUL5, RNF7\/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: LRRC41; MUF1; PP7759; Leucine-rich repeat-containing protein 41; Protein Muf1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 80kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10489\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q15345\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: nucleus, cytoplasm, membrane,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202093834419,"sku":"ES2726-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202093867187,"sku":"ES2726-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_48f86763-57b8-4777-9e8a-60efe579e972.png?v=1767121733","url":"https:\/\/afsbio.com\/products\/lrrc41-rabbit-pab-es2726","provider":"AFSBio Inc.","version":"1.0","type":"link"}