{"product_id":"lrrk2-monoclonal-antibody-bt-mca4227","title":"LRRK2 Monoclonal Antibody - BT-MCA4227","description":"\u003cp\u003eLRRK2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4227-50, BT-MCA4227-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: LRRK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2A4B12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LRRK2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human LRRK2 (AA: 300-530) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 286kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q5S007\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PARK8, RIPK7, ROCO2, AURA17, DARDARIN\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 120892\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238520185011,"sku":"BT-MCA4227-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238520217779,"sku":"BT-MCA4227-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1caf26d8-f61d-47c3-854c-295d0eaf5e8e.png?v=1769382093","url":"https:\/\/afsbio.com\/products\/lrrk2-monoclonal-antibody-bt-mca4227","provider":"AFSBio Inc.","version":"1.0","type":"link"}