{"product_id":"lsm4-polyclonal-antibody-bs8083","title":"LSM4 Polyclonal Antibody-BS8083","description":"\u003cp\u003eLSM4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS8083-50, BS8083-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9Y4Z0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1\/2 and the exonuclease, Xm1.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: LSM4 polyclonal antibody detects endogenous levels of LSM4 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of LSm4 expression in K562 (A), NIH3T3 (B) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: U6 snRNA-associated Sm-like protein LSm4; Glycine-rich protein; GRP; LSM4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human LSM4.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42946887975091,"sku":"BS8083-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42946888007859,"sku":"BS8083-100","price":576.38,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3181c4ec-ce3e-414a-93eb-27c5aa2d7fa5.jpg?v=1704884536","url":"https:\/\/afsbio.com\/products\/lsm4-polyclonal-antibody-bs8083","provider":"AFSBio Inc.","version":"1.0","type":"link"}