{"product_id":"lt-β-v211-polyclonal-antibody-bs2038","title":"LT-β (V211) Polyclonal Antibody-BS2038","description":"\u003cp\u003eLT-β (V211) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2038-50, BS2038-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q06643\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IHC IF\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-α, also known as TNF−β) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-β (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-α, and the ligand for the CD40 receptor. LT-α is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-β. LT-β, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-α to the cell surface. A TNF receptor-related protein, the LT-β receptor (also known as TNFC receptor), is the human receptor for the LT-α\/LT-β heterotrimer. There are two LT-β isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-β maps to the major histocompatibility complex region on human chromosome 6p21.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: LT-β (V211) polyclonal antibody detects endogenous levels of LT-β protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of LT-β (V211) pAb at 1:500 dilution\u003cbr\u003e\nLane1:H9C2 whole cell lysate(40ug)\u003cbr\u003e\nLane2:MEF whole cell lysate(40ug)\u003cbr\u003e\nLane3:Hela whole cell lysate(40ug)\u003cbr\u003e\nLane4:HEK293T whole cell lysate(40ug)\u003cbr\u003e\nLane5:HepG2 whole cell lysate(40ug)\u003cbr\u003e\nLane6:A549 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3; LTB; TNFC; TNFSF3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 200-250 of Human LT-β.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910477746355,"sku":"BS2038-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910477779123,"sku":"BS2038-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cc8c4559-3f34-4f1a-9f3b-b83d11d8f7e1.jpg?v=1703093215","url":"https:\/\/afsbio.com\/products\/lt-%ce%b2-v211-polyclonal-antibody-bs2038","provider":"AFSBio Inc.","version":"1.0","type":"link"}