{"product_id":"lt-beta-polyclonal-antibody-bt-ap10991","title":"LT-beta Polyclonal Antibody - BT-AP10991","description":"\u003cp\u003eLT-beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10991-20, BT-AP10991-50, BT-AP10991-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1\/beta 2 complex (e.g. 1 molecule alpha\/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2\/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LTB\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Lymphotoxin-beta\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q06643; Mouse: P41155\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Lymphotoxin-beta;LT-beta;Tumor necrosis factor C;TNF-C;Tumor necrosis factor ligand superfamily member 3; Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4050; Mouse: 16994\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239208018099,"sku":"BT-AP10991-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239208050867,"sku":"BT-AP10991-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239208083635,"sku":"BT-AP10991-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_83753474-1a86-40c2-a052-a00958ea9bea.png?v=1769390608","url":"https:\/\/afsbio.com\/products\/lt-beta-polyclonal-antibody-bt-ap10991","provider":"AFSBio Inc.","version":"1.0","type":"link"}