{"product_id":"ltor3-polyclonal-antibody-bt-ap11000","title":"LTOR3 Polyclonal Antibody - BT-AP11000","description":"\u003cp\u003eLTOR3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11000-20, BT-AP11000-50, BT-AP11000-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1\/MEK1, MAP kinase MAPK3\/ERK1, and MAP kinase MAPK1\/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LAMTOR3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Ragulator complex protein LAMTOR3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UHA4; Mouse: O88653; Rat: Q5U204\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ragulator complex protein LAMTOR3;Late endosomal\/lysosomal adaptor and MAPK and MTOR activator 3;MEK-binding partner 1;Mp1;Mitogen-activated protein kinase kinase 1-interacting protein 1;Mito\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8649\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239209033907,"sku":"BT-AP11000-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239209066675,"sku":"BT-AP11000-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239209099443,"sku":"BT-AP11000-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5df26055-8735-484e-b837-7f03bf3b7700.png?v=1769390619","url":"https:\/\/afsbio.com\/products\/ltor3-polyclonal-antibody-bt-ap11000","provider":"AFSBio Inc.","version":"1.0","type":"link"}