{"product_id":"lws-rabbit-polyclonal-antibody-es8842","title":"LWS Rabbit Polyclonal Antibody - ES8842","description":"\u003cp\u003eLWS Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8842-50, ES8842-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: retinoid X receptor gamma(RXRG) Homo sapiens This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human LWS. at AA range: 380-420\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: LWS\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of LWS\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in aortic endothelial cells (at protein level),\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 50kD\u003c\/p\u003e\n\n\u003cp\u003eFields: PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Transcriptional misregulation in cancer, Chemical carcinogenesis - receptor activation, Thyroid cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer, Lipid and atherosclerosis\u003c\/p\u003e\n\n\u003cp\u003eFunction: Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data\u003cbr\u003e\nDomain: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain\u003cbr\u003e\nFunction: Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA)\u003cbr\u003e\nSimilarity: Belongs to the nuclear hormone receptor family. NR2 subfamily\u003cbr\u003e\nSimilarity: Contains 1 nuclear receptor DNA-binding domain\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus Cytoplasm\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: RXRG NR2B3\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: LWS\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 20183\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P28705\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46313905291443,"sku":"ES8842-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46313905324211,"sku":"ES8842-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/lws-rabbit-polyclonal-antibody-es8842","provider":"AFSBio Inc.","version":"1.0","type":"link"}