{"product_id":"lxn-polyclonal-antibody-e-ab-10437","title":"LXN Polyclonal Antibody - E-AB-10437","description":"\u003cp\u003eLXN Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10437-60, E-AB-10437-120, E-AB-10437-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: LXN\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ECI; Endogenous carboxypeptidase inhibitor; Latexin; Latexin protein; LXN; LXN; MUM; Protein MUM; TCI; Tissue carboxypeptidase inhibitor\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Immunology, Stem Cells, Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9BS40\u003c\/p\u003e\n\n\u003cp\u003eBackground: Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A\/B MCPs.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.6 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human LXN\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:5000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 26kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136020840627,"sku":"E-AB-10437-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136020873395,"sku":"E-AB-10437-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136020906163,"sku":"E-AB-10437-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8b23e238-a973-4721-bf0a-fdd505074375.png?v=1709987329","url":"https:\/\/afsbio.com\/products\/lxn-polyclonal-antibody-e-ab-10437","provider":"AFSBio Inc.","version":"1.0","type":"link"}