{"product_id":"lyag-rabbit-polyclonal-antibody-bt-ap03502","title":"LYAG Rabbit Polyclonal Antibody - BT-AP03502","description":"\u003cp\u003eLYAG Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03502-20, BT-AP03502-50, BT-AP03502-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes lysosomal alpha-glucosidase| which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II| also known as Pompeandapos;s disease| which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GAA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LYAG\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P10253; Mouse: P70699; Rat: Q6P7A9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LYAG; Lysosomal alpha-glucosidase; EC 3.2.1.20; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase;\u003c\/p\u003e \n\n\u003cp\u003eGeneID: Human: 2548; Mouse: 14387; Rat: 367562\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239003480243,"sku":"BT-AP03502-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239003513011,"sku":"BT-AP03502-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239003545779,"sku":"BT-AP03502-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f057c29f-7bca-4891-942c-71c3ab0624e1.png?v=1769387832","url":"https:\/\/afsbio.com\/products\/lyag-rabbit-polyclonal-antibody-bt-ap03502","provider":"AFSBio Inc.","version":"1.0","type":"link"}