{"product_id":"lyz-rabbit-monoclonal-antibody-bs9932m","title":"LYZ Rabbit Monoclonal Antibody -BS9932M","description":"\u003cp\u003eLYZ Rabbit Monoclonal Antibody\u003c\/p\u003e \n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS9932M-50, BS9932M-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P61626\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000-1:2000 \u003cbr\u003e\nICC\/IF: 1:50-1:200\u003cbr\u003e\nIHC: 1:200-1:500\u003c\/p\u003e \n\n\u003cp\u003eBackground: The origins of the lysozyme proteins date back an estimated 400 to 600 million years. Generally, lysozyme genes are relatively small, roughly 10 kilobases in length, and composed of four exons and three introns. Originally a bacteriolytic defensive agent, the function of this family of proteins adapted to serve a digestive function in its present forms. Lysozymes in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lysozyme C belongs to the glycosyl hydrolase 22 family, and newly identified relatives of Lysozyme C appear to possess anti-HIV activity, as well as preserved bacteriolytic function against Micrococcus lysodeikticus. Lysozyme C is capable of both hydrolysis and transglycosylation and also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides. Lysozyme C defects are a cause of amyloidosis VIII, also called familial visceral or Ostertag-type amyloidosis.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Protein A affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of LYZ and does not cross-react with related proteins.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of LYZ Rabbit mAb at 1:1000 dilution\u003cbr\u003e\n Lane 1: The kidney tissue lysate of Mouse\u003cbr\u003e\n Lane 2: HL-60 whole cell lysate, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Lysozyme antibody.Counter stained with hematoxylin., ICC staining Lysozyme in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Lysosyme; \u003cbr\u003e\nLysozyme (renal amyloidosis); \u003cbr\u003e\nLysozyme C; \u003cbr\u003e\nLysozyme C precursor; \u003cbr\u003e\nLYZ; \u003cbr\u003e\nLZM; \u003cbr\u003e\nRenal amyloidosis;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant antibody.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044034543795,"sku":"BS9932M-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044034576563,"sku":"BS9932M-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a7d668b1-8a21-446d-a6a4-698c9cc0c89b.jpg?v=1707738800","url":"https:\/\/afsbio.com\/products\/lyz-rabbit-monoclonal-antibody-bs9932m","provider":"AFSBio Inc.","version":"1.0","type":"link"}