{"product_id":"m6a-polyclonal-antibody-bt-ap05137","title":"M6A Polyclonal Antibody - BT-AP05137","description":"\u003cp\u003eM6A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05137-20, BT-AP05137-50, BT-AP05137-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GPM6A (Glycoprotein M6A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium channel activity. An important paralog of this gene is PLP1. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GPM6A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: M6A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31210\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P51674; Mouse: P35802; Rat: Q812E9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2823; Mouse: 234267; Rat: 306439\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239670145203,"sku":"BT-AP05137-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239670177971,"sku":"BT-AP05137-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239670210739,"sku":"BT-AP05137-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_88d4a1db-bffe-4b41-99d3-9569a2ecf407.png?v=1769397823","url":"https:\/\/afsbio.com\/products\/m6a-polyclonal-antibody-bt-ap05137","provider":"AFSBio Inc.","version":"1.0","type":"link"}