{"product_id":"mad1-mad1l1-polyclonal-antibody-bs6186","title":"MAD1\/MAD1L1 Polyclonal Antibody-BS6186","description":"\u003cp\u003eMAD1\/MAD1L1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50 µl, 100 µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6186-50, BS6186-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9Y6D9\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eMAD1\/MAD1L1 Polyclonal Antibody-BS6186\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB,1:500 - 1:2000  |  IF\/ICC,1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 95kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cell lines, using MAD1\/MAD1\/MAD1L1 antibody at 1:1000 dilution.\u003cbr\u003e\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\u003cbr\u003e\nLysates\/proteins: 25ug per lane.\u003cbr\u003e\nBlocking buffer: 3% non-fat dry milk in TBST.\u003cbr\u003e\nDetection: ECL Basic Kit., Immunofluorescence analysis of U2OS cells using MAD1\/MAD1\/MAD1L1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: MAD1L1; MAD1; PIG9; TP53I9; TXBP181\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human MAD1\/MAD1\/MAD1L1(NP_001013859.1).\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962848153779,"sku":"BS6186-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962848186547,"sku":"BS6186-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2615cb02-f3a8-43e5-93b7-9cef876d2802.jpg?v=1705319316","url":"https:\/\/afsbio.com\/products\/mad1-mad1l1-polyclonal-antibody-bs6186","provider":"AFSBio Inc.","version":"1.0","type":"link"}