{"product_id":"mafk-monoclonal-antibody-mb66733","title":"MAFK Monoclonal Antibody-MB66733","description":"\u003cp\u003eMAFK Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66733-50, MB66733-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O60675\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000), FC (1\/10 - 1\/50)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Members of the Maf family of basic region\/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter.c-Maf (Maf-2) and the closely related family members Neural retina leucine zipper (Nrl), L-Maf and Krml1\/MafB (Maf-1) all bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The three small Maf family proteins MafF, MafG and MafK are components of NF-E2 which function as heterodimers with the large tissue restricted subunit of NF-E2 called p45, and furthermore are implicated in the transcriptional regulation of many erythroid-specific genes. MafG is ubiquitously expressed, with highest expression in the VMS, heart and skeletal muscle; its expression is induced in response to stress. MafK, also designated NF-E2 p18, is primarily expressed during development in mesenchymal and hematopoietic cells and neurons. MafK heterodimerizes with NF-E2 and various CNC proteins. MafF is most abundantly expressed in the lung and is thought to compensate for loss of function mutations in MafG and MafK.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of MAFK protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of MAFK expression in Jurkat (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 16 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide of human MAFK. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906372276403,"sku":"MB66733-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906372309171,"sku":"MB66733-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bf2d54bd-1c54-4f65-a6b2-d19cd289b7dd.jpg?v=1702918834","url":"https:\/\/afsbio.com\/products\/mafk-monoclonal-antibody-mb66733","provider":"AFSBio Inc.","version":"1.0","type":"link"}