{"product_id":"magel2-polyclonal-antibody-e-ab-13399","title":"MAGEL2 Polyclonal Antibody - E-AB-13399","description":"\u003cp\u003eMAGEL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13399-60, E-AB-13399-120, E-AB-13399-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MAGEL2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Mage-l2; MAGE-like 2; MAGE-like protein 2; MAGEL2; melanoma antigen-like gene 2; NDNL1; Necdin like protein 1; necdin-like 1; nM15; ns7; Protein nM15; PWLS\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UJ55\u003c\/p\u003e\n\n\u003cp\u003eBackground: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.8 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human MAGEL2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124130087091,"sku":"E-AB-13399-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124130119859,"sku":"E-AB-13399-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124130152627,"sku":"E-AB-13399-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_94725dce-4df5-4e78-8500-318db272a433.png?v=1709724349","url":"https:\/\/afsbio.com\/products\/magel2-polyclonal-antibody-e-ab-13399","provider":"AFSBio Inc.","version":"1.0","type":"link"}