{"product_id":"mal-polyclonal-antibody-bt-ap11085","title":"MAL Polyclonal Antibody - BT-AP11085","description":"\u003cp\u003eMAL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11085-20, BT-AP11085-50, BT-AP11085-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and\/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Cancer; Stem cells; Cell biology; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Myelin and lymphocyte protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P21145; Mouse: O09198; Rat: Q64349\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Myelin and lymphocyte protein;T-lymphocyte maturation-associated protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4118\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239214604467,"sku":"BT-AP11085-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239214637235,"sku":"BT-AP11085-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239214670003,"sku":"BT-AP11085-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_88645187-514d-4520-a078-33a619c92e3d.png?v=1769390680","url":"https:\/\/afsbio.com\/products\/mal-polyclonal-antibody-bt-ap11085","provider":"AFSBio Inc.","version":"1.0","type":"link"}