{"product_id":"map2k5-monoclonal-antibody-bt-mca4461","title":"MAP2K5 Monoclonal Antibody - BT-MCA4461","description":"\u003cp\u003eMAP2K5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4461-50, BT-MCA4461-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7\/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3\/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAP2K5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5H11B10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MAP2K5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 50kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q13163\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MEK5, MAPKK5, PRKMK5, HsT17454\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5607\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238562455731,"sku":"BT-MCA4461-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238562488499,"sku":"BT-MCA4461-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9c9a7d3f-252e-49bc-a9cd-717899286784.png?v=1769382596","url":"https:\/\/afsbio.com\/products\/map2k5-monoclonal-antibody-bt-mca4461","provider":"AFSBio Inc.","version":"1.0","type":"link"}