{"product_id":"mapkapk-2-polyclonal-antibody-bt-ap05212","title":"MAPKAPK-2 Polyclonal Antibody - BT-AP05212","description":"\u003cp\u003eMAPKAPK-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05212-20, BT-AP05212-50, BT-AP05212-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: MAPKAPK2 (mitogen-activated protein kinase-activated protein kinase 2) encodes a member of the Ser\/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAPKAPK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MAPKAPK-2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 45568\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49137; Mouse: P49138\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MAPKAPK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9261; Mouse: 17164\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239677845683,"sku":"BT-AP05212-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239677878451,"sku":"BT-AP05212-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239677911219,"sku":"BT-AP05212-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_23996a3d-8374-44a9-a591-dd2a780e401c.png?v=1769397877","url":"https:\/\/afsbio.com\/products\/mapkapk-2-polyclonal-antibody-bt-ap05212","provider":"AFSBio Inc.","version":"1.0","type":"link"}