{"product_id":"marh8-polyclonal-antibody-bt-ap11124","title":"MARH8 Polyclonal Antibody - BT-AP11124","description":"\u003cp\u003eMARH8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11124-20, BT-AP11124-50, BT-AP11124-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MARH8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: E3 ubiquitin-protein ligase MARCH8\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q5T0T0; Mouse: Q9DBD2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: E3 ubiquitin-protein ligase MARCH8;EC 6.3.2.-;Cellular modulator of immune recognition;c-MIR;Membrane-associated RING finger protein 8;Membrane-associated RING-CH protein VIII;MARCH-VIII;\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 220972\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239215980723,"sku":"BT-AP11124-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239216013491,"sku":"BT-AP11124-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239216046259,"sku":"BT-AP11124-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c1edf677-b472-4f0d-95e8-c91943ae94e7.png?v=1769390698","url":"https:\/\/afsbio.com\/products\/marh8-polyclonal-antibody-bt-ap11124","provider":"AFSBio Inc.","version":"1.0","type":"link"}