{"product_id":"mark1-2-3-4-rabbit-pab-es2746","title":"MARK1\/2\/3\/4 rabbit pAb - ES2746","description":"\u003cp\u003eMARK1\/2\/3\/4 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2746-50, ES2746-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39., function:May play a role in cytoskeletal stability., similarity:Belongs to the protein kinase superfamily. CAMK Ser\/Thr protein kinase family. MARK subfamily., similarity:Contains 1 KA1 (kinase-associated) domain., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UBA domain., subcellular location:Appears to localize to an intracellular network., tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MARK1; KIAA1477; MARK; Serine\/threonine-protein kinase MARK1; MAP\/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine\/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP\/microtubule affin\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Monkey\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MARK1\/2\/3\/4. AA range:181-230\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 89kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4139\/2011\/4140\/57787\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9P0L2\/Q7KZI7\/P27448\/Q96L34\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, dendrite. Appears to localize to an intracellular network.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202095177907,"sku":"ES2746-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202095210675,"sku":"ES2746-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_fa6d7b1a-8d94-414d-8850-aeaf6106698c.png?v=1767121775","url":"https:\/\/afsbio.com\/products\/mark1-2-3-4-rabbit-pab-es2746","provider":"AFSBio Inc.","version":"1.0","type":"link"}