{"product_id":"mast205-rabbit-pab-es2749","title":"MAST205 rabbit pAb - ES2749","description":"\u003cp\u003eMAST205 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2749-50, ES2749-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:Appears to link the dystrophin\/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation., PTM:Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination., similarity:Belongs to the protein kinase superfamily. AGC Ser\/Thr protein kinase family., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 protein kinase domain., subcellular location:Recruited to the sub-membranous area on interaction with PC-LKC., tissue specificity:Abundant in the testis.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MAST2; KIAA0807; MAST205; Microtubule-associated serine\/threonine-protein kinase 2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MAST2. AA range:1201-1250\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 196kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 23139\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q6P0Q8\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the sub-membranous area on interaction with CDHR2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202095505587,"sku":"ES2749-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202095538355,"sku":"ES2749-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6da06f28-d39c-43bb-932b-592064c5db89.png?v=1767121781","url":"https:\/\/afsbio.com\/products\/mast205-rabbit-pab-es2749","provider":"AFSBio Inc.","version":"1.0","type":"link"}