{"product_id":"maxikbeta2-polyclonal-antibody-bt-ap05253","title":"MaxiKBeta2 Polyclonal Antibody - BT-AP05253","description":"\u003cp\u003eMaxiKBeta2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05253-20, BT-AP05253-50, BT-AP05253-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. Calcium-activated potassium channel subunit beta-2 encoded by KCNMB2 is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCNMB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MaxiKbeta2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27130\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y691; Mouse: Q9CZM9; Rat: Q811Q0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KCNMB2; Calcium-activated potassium channel subunit beta-2; BK channel subunit beta-2; BKbeta2; Hbeta2; Calcium-activated potassium channel; subfamily M subunit beta-2; Charybdotoxin receptor subunit\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10242; Mouse: 72413; Rat: 294961\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239680598195,"sku":"BT-AP05253-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239680630963,"sku":"BT-AP05253-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239680663731,"sku":"BT-AP05253-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8531b629-18ba-4efa-8583-0b783be15f62.png?v=1769397918","url":"https:\/\/afsbio.com\/products\/maxikbeta2-polyclonal-antibody-bt-ap05253","provider":"AFSBio Inc.","version":"1.0","type":"link"}