{"product_id":"mbtps2-polyclonal-antibody-e-ab-52057","title":"MBTPS2 Polyclonal Antibody - E-AB-52057","description":"\u003cp\u003eMBTPS2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52057-60, E-AB-52057-120, E-AB-52057-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MBTPS2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BRESEK; Endopeptidase S2P; IFAP; KFSDX; MBTP2; MBTPS2; Membrane bound transcription factor site 2 protease; membrane-bound transcription factor peptidase; site 2; membrane-bound transcription factor protease; site 2; Membrane-bound transcription factor site-2 protease; S2P; S2P endopeptidase; Site 2 protease; SREBPs intramembrane protease; Sterol regulatory element-binding proteins intramembrane protease\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Cardiovascular, Metabolism, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O43462\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.9 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human MBTPS2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:10-1:50, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 57 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143940767923,"sku":"E-AB-52057-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143940800691,"sku":"E-AB-52057-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143940833459,"sku":"E-AB-52057-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_00766b34-e8cf-4f76-8e5b-35207e27de07.png?v=1710244041","url":"https:\/\/afsbio.com\/products\/mbtps2-polyclonal-antibody-e-ab-52057","provider":"AFSBio Inc.","version":"1.0","type":"link"}