{"product_id":"mcm2-phospho-ser139-rabbit-polyclonal-antibody-bt-ap03565","title":"MCM2 (Phospho-Ser139) Rabbit Polyclonal Antibody - BT-AP03565","description":"\u003cp\u003eMCM2 (Phospho-Ser139) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03565-20, BT-AP03565-50, BT-AP03565-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4| 6| and 7| and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated| and thus regulated by| protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found| but the full-length nature of some variants has not been defined.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: MCM2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MCM2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49736; Mouse: P97310\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MCM2;Ser139; DNA replication licensing factor MCM2; EC 3.6.4.12; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4171; Mouse: 17216\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239005249715,"sku":"BT-AP03565-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239005282483,"sku":"BT-AP03565-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239005315251,"sku":"BT-AP03565-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_93224500-05a8-4ebd-94bf-26fd5b713094.png?v=1769387855","url":"https:\/\/afsbio.com\/products\/mcm2-phospho-ser139-rabbit-polyclonal-antibody-bt-ap03565","provider":"AFSBio Inc.","version":"1.0","type":"link"}