{"product_id":"mcm7-polyclonal-antibody-ra27095","title":"MCM7 Polyclonal Antibody - RA27095","description":"\u003cp\u003eMCM7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27095-50, RA27095-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: minichromosome maintenance complex component 7 (MCM7) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1\/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC-p 1:50-200, WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: DNA replication licensing factor MCM7 (EC 3.6.4.12;CDC47 homolog;P1.1-MCM3)\u003c\/p\u003e \n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section) ; WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4176\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 79\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P33993\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121390051507,"sku":"RA27095-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121390084275,"sku":"RA27095-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f8506845-c6f9-4640-80a7-234aaabb2f5b.png?v=1773347152","url":"https:\/\/afsbio.com\/products\/mcm7-polyclonal-antibody-ra27095","provider":"AFSBio Inc.","version":"1.0","type":"link"}