{"product_id":"mdga1-rabbit-polyclonal-antibody-es10944","title":"MDGA1 Rabbit Polyclonal Antibody - ES10944","description":"\u003cp\u003eMDGA1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10944-50, ES10944-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: MDGA1,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: MDGA1 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 105kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Required for radial migration of cortical neurons in the superficial layer of the neocortex. Similarity: Contains 1 fibronectin type-III domain. Similarity: Contains 1 MAM domain. Similarity: Contains 6 Ig-like (immunoglobulin-like) domains. Subcellular Location: Associated with lipid rafts. Subunit: Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle. Tissue Specificity: Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.\u003c\/p\u003e \n\n\u003cp\u003eSubcellular Location: Cell membrane, Lipid-anchor, GPI-anchor Associated with lipid rafts.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: MDGA1, MAMDC3\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1, GPI and MAM protein, GPIM, Glycosylphosphatidylinositol-MAM, MAM domain-containing protein 3\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 266727\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q8NFP4\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q0PMG2\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P85171\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825498710195,"sku":"ES10944-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825498742963,"sku":"ES10944-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/mdga1-rabbit-polyclonal-antibody-es10944","provider":"AFSBio Inc.","version":"1.0","type":"link"}