{"product_id":"mdr3-polyclonal-antibody-bt-ap11206","title":"MDR3 Polyclonal Antibody - BT-AP11206","description":"\u003cp\u003eMDR3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11206-20, BT-AP11206-50, BT-AP11206-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR\/TAP subfamily. Members of the MDR\/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ABCB4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Multidrug resistance protein 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P21439; Mouse: P21440; Rat: Q08201\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Multidrug resistance protein 3;EC 3.6.3.44;ATP-binding cassette sub-family B member 4;P-glycoprotein 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5244\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239218995379,"sku":"BT-AP11206-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239219028147,"sku":"BT-AP11206-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239219060915,"sku":"BT-AP11206-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_27bfb289-6778-4f53-9a1e-fea782e2011b.png?v=1769390741","url":"https:\/\/afsbio.com\/products\/mdr3-polyclonal-antibody-bt-ap11206","provider":"AFSBio Inc.","version":"1.0","type":"link"}