{"product_id":"me2-polyclonal-antibody-bt-ap05306","title":"ME2 Polyclonal Antibody - BT-AP05306","description":"\u003cp\u003eME2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05306-20, BT-AP05306-50, BT-AP05306-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ME2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ME2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 65444\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P23368; Mouse: Q99KE1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4200\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239684956339,"sku":"BT-AP05306-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239684989107,"sku":"BT-AP05306-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239685021875,"sku":"BT-AP05306-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_93044966-05d2-4f67-84e4-4e247fb24d2b.png?v=1769397980","url":"https:\/\/afsbio.com\/products\/me2-polyclonal-antibody-bt-ap05306","provider":"AFSBio Inc.","version":"1.0","type":"link"}