{"product_id":"mef2c-rabbit-pab-a12385","title":"MEF2C Rabbit pAb - A12385","description":"\u003cp\u003eMEF2C Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A12385-20, A12385-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF-P, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 51kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 45kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4208\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q06413\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NEDHSIL; DEL5q14.3; C5DELq14.3; MEF2C\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:100 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Endocrine Metabolism, AMPK Signaling Pathway, Immunology Inflammation, B Cell Receptor Signaling Pathway, Neuroscience, Calcium Signaling, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Heart, Cardiogenesis, Hypertrophy.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: MEF2C\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189522391219,"sku":"A12385-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189522423987,"sku":"A12385-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b18df1d7-4e60-4063-8469-0dcfd95a0821.png?v=1766428941","url":"https:\/\/afsbio.com\/products\/mef2c-rabbit-pab-a12385","provider":"AFSBio Inc.","version":"1.0","type":"link"}