{"product_id":"mek-5-rabbit-pab-es20665","title":"MEK-5 rabbit pAb - ES20665","description":"\u003cp\u003eMEK-5 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20665-50, ES20665-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7\/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3\/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK\/ERK kinase 5; MEK 5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000-2000 IHC: 1:200-500\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein of MEK-5\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 49kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5067\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q13163\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: nucleus, cytoplasm, spindle, cytosol,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201966071987,"sku":"ES20665-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201966104755,"sku":"ES20665-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6abb6db2-aed2-4f32-a8b1-2016f6d9274d.png?v=1767119027","url":"https:\/\/afsbio.com\/products\/mek-5-rabbit-pab-es20665","provider":"AFSBio Inc.","version":"1.0","type":"link"}