{"product_id":"mek-kinase-1-polyclonal-antibody-ra27146","title":"MEK Kinase-1 Polyclonal Antibody - RA27146","description":"\u003cp\u003eMEK Kinase-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA27146-50, RA27146-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: mitogen-activated protein kinase kinase kinase 1 (MAP3K1) Homo sapiens The protein encoded by this gene is a serine\/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: MAP3K1; MAPKKK1; MEKK; MEKK1; Mitogen-activated protein kinase kinase kinase 1; MAPK\/ERK kinase kinase 1; MEK kinase 1; MEKK 1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4214\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 165\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13233\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121392738483,"sku":"RA27146-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121392771251,"sku":"RA27146-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1c951370-1d57-4ff0-9ced-5b3b94c6b349.png?v=1773347174","url":"https:\/\/afsbio.com\/products\/mek-kinase-1-polyclonal-antibody-ra27146","provider":"AFSBio Inc.","version":"1.0","type":"link"}