{"product_id":"mek1-phospho-t292-polyclonal-antibody-bs94047","title":"MEK1 (Phospho-T292) Polyclonal Antibody-BS94047","description":"\u003cp\u003eMEK1 (Phospho-T292) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS94047-50, BS94047-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q02750(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003c\/p\u003e\n\n\u003cp\u003eBackground: A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-MEK1 (T292) on Daudi cellsLysates using anti-Phospho-MEK1 (T292) antibody at 1\/1,000 dilution.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 43 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MEK1 (Phospho-T292) polyclonal antibody detects endogenous levels of MEK1 protein only when phosphorylated at T292.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: MAP kinase kinase 1, MAPKK 1, MKK1, MEK 1, MAP2K1, Dual specificity mitogen activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAP kinase\/Erk kinase 1, MAP2K1, MAPK\/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEKK1, Mitogen activated protein kinase kinase 1, MKK 1, MKK1, MP2K1, PRKMK1, Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1), Protein kinase mitogen activated, kinase 1,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr292 of human MEK1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939210105011,"sku":"BS94047-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939210137779,"sku":"BS94047-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_90a46ad5-ad3f-429f-8298-3da51fe0c551.jpg?v=1704545130","url":"https:\/\/afsbio.com\/products\/mek1-phospho-t292-polyclonal-antibody-bs94047","provider":"AFSBio Inc.","version":"1.0","type":"link"}