{"product_id":"mfn2-polyclonal-antibody-e-ab-32025","title":"MFN2 Polyclonal Antibody - E-AB-32025","description":"\u003cp\u003eMFN2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-32025-60, E-AB-32025-120, E-AB-32025-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Mfn2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CMT2A; CMT2A2; CPRP 1; CPRP1; EC 3.6.5.-; Fzo; HSG; hyperplasia suppressor gene; Hypertension related protein 1; KIAA0214; MARF; MFN 2; Mfn2; MFN2; Mitochondrial assembly regulatory factor; Mitofusin-2; Mitofusin2; Transmembrane GTPase MFN2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O95140\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from the Internal region of human Mfn2.\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 86kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 86kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146015441075,"sku":"E-AB-32025-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146015473843,"sku":"E-AB-32025-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146015506611,"sku":"E-AB-32025-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_52b9a8d5-774c-4cdd-998e-c9850fd5cb00.png?v=1710289830","url":"https:\/\/afsbio.com\/products\/mfn2-polyclonal-antibody-e-ab-32025","provider":"AFSBio Inc.","version":"1.0","type":"link"}