{"product_id":"mglur-6-a865-polyclonal-antibody-bs1146","title":"mGluR-6 (A865) Polyclonal Antibody-BS1146","description":"\u003cp\u003emGluR-6 (A865) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1146-50, BS1146-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O15303\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eBackground: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: mGluR6 (A865) polyclonal antibody detects endogenous levels of mGluR6 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of mGluR-6 (A865) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: Hela cell lysate\u003cbr\u003e\nLane 2: NIH-3T3 cell lysate\u003cbr\u003e\nLane 3: Raw264.7 cell lysate\u003cbr\u003e\nLane 4: H9C2 cell lysate, Immunohistochemistry (IHC) analyzes of mGluR-6 (A865) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 100 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 841-890 of Human mGluR-6.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953207447731,"sku":"BS1146-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953207480499,"sku":"BS1146-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1d8001d6-31b2-4d63-9a82-897611b50627.jpg?v=1705056771","url":"https:\/\/afsbio.com\/products\/mglur-6-a865-polyclonal-antibody-bs1146","provider":"AFSBio Inc.","version":"1.0","type":"link"}