{"product_id":"mhc-class-i-recombinant-rabbit-monoclonal-antibody-bs66218","title":"MHC class I Recombinant Rabbit Monoclonal Antibody - BS66218","description":"\u003cp\u003eMHC class I Recombinant Rabbit mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66218-50, BS66218-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The human leukocyte antigen (HLA) system is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell surface proteins are responsible for the regμlation of antigen-specific immunity in humans. HLA genes are highly polymorphic, allowing them to fine-tune the adaptive immune response. HLAs corresponding to MHC class I (HLA-A,  B, and C) present small peptide antigens from inside the cell, approximately 8 to 10 amino acids in length, to CD8+ T lymphocytes in order to activate a cytotoxic T cell response. HLAs corresponding to MHC class II (HLA-DP,  DM,  DO,  DQ, and DR) present antigens from outside of the cell, approximately 15 to 24 residues in length, to CD4+ T helper cells, which in turn secrete cytokines and stimμlate B cells to produce antibodies to that specific antigen. HLAs corresponding to MHC class III encode components of the complement system.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HLAA, HLA class I histocompatibility antigen, A-1 alpha chain, MHC class I antigen A*1, HLAB, HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7, HLAA, HLA class I histocompatibility antigen, A-68 alpha chain, Aw-68, HLA class I histocompatibility antigen, A-28 alpha chain, MHC class I antigen A*68, HLAA, HLA class I histocompatibility antigen, A-2 alpha chain, MHC class I antigen A*2, HLAA, HLA class I histocompatibility antigen, A-11 alpha chain, MHC class I antigen A*11, HLAA, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen A*30, HLAA, HLA class I histocompatibility antigen, A-26 alpha chain, MHC class I antigen A*26\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within human MHC class I.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB, 1:500 - 1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from cell cμlture supernatant by protein A+G and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MHC class I Monoclonal Antibody detects endogenous levels of MHC class I protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 41 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P30443, P01889, P01891, P01892, P13746, P16188, P30450\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938582126771,"sku":"BS66218-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938582159539,"sku":"BS66218-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/mhc-class-i-recombinant-rabbit-monoclonal-antibody-bs66218","provider":"AFSBio Inc.","version":"1.0","type":"link"}