{"product_id":"midn-polyclonal-antibody-e-ab-12568","title":"MIDN Polyclonal Antibody - E-AB-12568","description":"\u003cp\u003eMIDN Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-12568-60, E-AB-12568-120, E-AB-12568-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MIDN\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Midbrain nucleolar protein; midn; MIDN; Midnolin\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q504T8\u003c\/p\u003e\n\n\u003cp\u003eBackground: Expression of themidnolingene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. Themidnolinencodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of themidnolinwas studied by usingmidnolin-green fluorescent protein (GFP) fusion proteins.Midnolinwas found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of themidnolin.May be involved in regulation of genes related to neurogenesis in the nucleolus\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human MIDN\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136256835763,"sku":"E-AB-12568-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136256868531,"sku":"E-AB-12568-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136256901299,"sku":"E-AB-12568-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_78da78ee-d4b6-4365-846c-f8c15e61e7f7.png?v=1709988560","url":"https:\/\/afsbio.com\/products\/midn-polyclonal-antibody-e-ab-12568","provider":"AFSBio Inc.","version":"1.0","type":"link"}