{"product_id":"mk-rabbit-polyclonal-antibody-es3907","title":"MK Rabbit Polyclonal Antibody - ES3907","description":"\u003cp\u003eMK Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3907-50, ES3907-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MDK, MK1, NEGF2, Midkine, MK, Amphiregulin-associated protein, ARAP, Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MDK. AA range:94-143\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: MK\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: MK Polyclonal Antibody detects endogenous levels of MK protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in various tumor cell lines, In insulinoma tissue predominantly expressed in precancerous lesions,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 18kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development\u003cbr\u003e\nInduction: By heparin and retinoic acid\u003cbr\u003e\nSimilarity: Belongs to the pleiotrophin family\u003cbr\u003e\nSubunit: Homodimer\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: MDK\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Midkine\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P12025\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 81517\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q9R1S9\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316513034419,"sku":"ES3907-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316513067187,"sku":"ES3907-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/mk-rabbit-polyclonal-antibody-es3907","provider":"AFSBio Inc.","version":"1.0","type":"link"}