{"product_id":"mkk7-phospho-ser271-thr275-rabbit-pab-es14942","title":"MKK7 (phospho-Ser271\/Thr275) rabbit pAb - ES14942","description":"\u003cp\u003eMKK7 (phospho-Ser271\/Thr275) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES14942-50, ES14942-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8\/JNK1 and MAPK9\/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1\/MEKK1, MAP3K2\/MEKK2, MAP3K3\/MEKK5, and MAP4K2\/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK\/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized phosho peptide around human MKK7 (Ser271 and Thr275)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 47kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5609\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O14733\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202410602675,"sku":"ES14942-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202410635443,"sku":"ES14942-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_88ececb1-85ac-42e5-9d80-ff8419715f01.png?v=1767128583","url":"https:\/\/afsbio.com\/products\/mkk7-phospho-ser271-thr275-rabbit-pab-es14942","provider":"AFSBio Inc.","version":"1.0","type":"link"}