{"product_id":"mkks-polyclonal-antibody-e-ab-91125","title":"MKKS Polyclonal Antibody - E-AB-91125","description":"\u003cp\u003eMKKS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91125-60, E-AB-91125-120, E-AB-91125-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MKKS\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MKKS; BBS6; HMCS; KMS; MKS\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NPJ1\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human MKKS\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 62kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 62kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146592190643,"sku":"E-AB-91125-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146592223411,"sku":"E-AB-91125-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146592256179,"sku":"E-AB-91125-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e85e48e9-eaf7-4942-9dc1-7424f2555328.png?v=1710298017","url":"https:\/\/afsbio.com\/products\/mkks-polyclonal-antibody-e-ab-91125","provider":"AFSBio Inc.","version":"1.0","type":"link"}