{"product_id":"mkks-rabbit-polyclonal-antibody-bt-ap11334","title":"MKKS Rabbit Polyclonal Antibody - BT-AP11334","description":"\u003cp\u003eMKKS Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11334-20, BT-AP11334-50, BT-AP11334-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome| which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6| also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Metabolism; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MKKS\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: MKKS\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NPJ1; Mouse: Q9JI70\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MKKS; McKusick-Kaufman\/Bardet-Biedl syndromes putative chaperonin; Bardet-Biedl syndrome 6 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8195; Mouse: 59030\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239005872307,"sku":"BT-AP11334-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239005905075,"sku":"BT-AP11334-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239005937843,"sku":"BT-AP11334-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fbd81551-3465-4d46-8c8e-259c59ed2df6.png?v=1769387863","url":"https:\/\/afsbio.com\/products\/mkks-rabbit-polyclonal-antibody-bt-ap11334","provider":"AFSBio Inc.","version":"1.0","type":"link"}