{"product_id":"mkl1-polyclonal-antibody-e-ab-66247","title":"MKL1 Polyclonal Antibody - E-AB-66247","description":"\u003cp\u003eMKL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66247-60, E-AB-66247-120, E-AB-66247-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MKL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MKL1; BSAC; MAL; MRTF-A\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q969V6\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human MKL1 (NP_065882.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 98kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 150kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146411802803,"sku":"E-AB-66247-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146411835571,"sku":"E-AB-66247-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146411868339,"sku":"E-AB-66247-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0617c88b-f058-4289-836e-d2b92fb9336e.png?v=1710295111","url":"https:\/\/afsbio.com\/products\/mkl1-polyclonal-antibody-e-ab-66247","provider":"AFSBio Inc.","version":"1.0","type":"link"}