{"product_id":"mkl1-rabbit-pab-a12598","title":"MKL1 Rabbit pAb - A12598","description":"\u003cp\u003eMKL1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A12598-20, A12598-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 99kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 145kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 57591\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q969V6\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MAL; MKL; BSAC; MKL1; MRTF-A\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Transcription Factors, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cytoskeleton, Endocrine Metabolism, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Heart, Cardiogenesis.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: MRTFA\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189530779827,"sku":"A12598-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189530812595,"sku":"A12598-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a41f596c-9c42-4a7d-b17b-748afcd676ea.png?v=1766429145","url":"https:\/\/afsbio.com\/products\/mkl1-rabbit-pab-a12598","provider":"AFSBio Inc.","version":"1.0","type":"link"}